Deputy Director
The Role
We're hiring a Deputy Director to help run MBDF. This is a co-leadership role: you'll partner with James Smith (our Executive Director) across strategy, operations, and organizational development. You'll have the authority and autonomy to shape your portfolio as we grow.
At baseline, you own operations, lead our strategic planning process and week-to-week goal setting, and ensure MBDF is executing well. But for the right person, the ceiling is much higher. We're a 10-person organization with ambitious goals—that means little bureaucracy, extensive ownership, and real influence over what we become.
The specific shape of this role will depend on who you are and what you're great at. We've also posted this job description as "Director of Operations" to reach candidates with deeper ops backgrounds. Both postings are pointing at the same role—we're looking for one senior leader to co-lead MBDF.
What you'll own
Operations
You'll oversee the core machinery that keeps MBDF running: finance, HR, compliance, event logistics, and grantmaking operations. You'll manage our Business Operations Lead, our Operations Associate, and the systems and vendors that support our Operations functions. This is a leadership role—we're hiring you to ensure these functions run well, not to do everything yourself. But we're a 10-person org, so senior leaders here roll up their sleeves when something needs doing.
Strategy & execution.
You'll drive our goal-setting and planning processes, help translate high-level priorities into concrete plans, and keep us accountable to what we said we'd do. When initiatives get stuck or complicated, you’ll help unblock them.
Organizational health.
You'll think holistically about how the team is structured, how communication flows, and whether we're building a culture where people can do great work. You'll be a thought partner to other leaders across MBDF—helping them navigate challenges and develop their teams.
Room to grow
The core of this role is operations and organizational leadership. But we're a small team, and our other functions—science, policy, communications, strategy—all could benefit from additional support and senior attention.
For the right person, there's scope to expand into these areas. You might help shape how we engage with policymakers, or guide our external communications, or support our science team's planning. Exactly what this looks like depends on your background and interests. We're excited to figure it out together.
About You
You're deeply motivated by MBDF's mission and excited to help a maturing organization take on the risks mirror life could pose.
You're an entrepreneurial leader who has managed diverse functions. You have strong judgment about stakeholders, reputation, and organizational priorities. You're the kind of person who can look at a messy situation involving external relationships, figure out what actually matters, and make a call.
You bring:
Demonstrated ability to make things happen. You don't just have good ideas—you've executed on them. You've got a track record of tackling hard problems and delivering.
Sound judgment on people and stakeholders. You're good at mentally modeling how others will react, what they care about, and how to navigate tricky situations. You've dealt with thorny stakeholder dynamics and come out the other side.
Comfort with an unusual portfolio. You don't need to be an expert in everything you oversee. You know how to manage functions where you're not the subject-matter expert, ask the right questions, and ensure good outcomes.
A bias toward ownership. You take responsibility for your portfolio end-to-end. When something isn't working, you fix it or flag it — you don't wait for someone else to notice.
Pragmatism about what matters. You balance ambition with practicality. You're the person who asks "but will this actually work?" and helps the team understand and navigate real constraints.
Comfort with ambiguity. You're energized rather than paralyzed by novel problems and blank slates. MBDF is a young organization tackling unprecedented challenges — you'll regularly encounter situations without playbooks.
Alignment with our mission. You want to work on problems that matter. You care deeply about understanding and addressing the potentially catastrophic risks of mirror life.
Experience & Skills
We're not looking for a unicorn. This role touches a lot of areas, and we don't expect you to be an expert in all of them. We're looking for a strong leader with good judgment who can grow with us.
That said, we're excited about candidates who bring some combination of:
Experience overseeing operations functions (finance, HR, compliance, events)—you don't need deep expertise in all of these areas, but you should be comfortable providing direction
Background in communications, stakeholder management, or public affairs—particularly where reputation and messaging matter
Strong instincts for project management and keeping many things on track
Experience managing and developing a small team
Comfort working with senior leadership and external stakeholders
Background in nonprofits, policy, science-adjacent orgs, or other mission-driven environments
Practicalities
Compensation: $180-210k USD + full benefits; exact offer will reflect experience and fit.
Location: Remote. MBDF is a fully remote organization.
Working hours: Must be available during core hours (10am-2pm ET) for overlap with team members across time zones.
Start: As soon as practical — applications reviewed on a rolling basis.
Reports to: Executive Director
MBDF is an equal opportunity employer committed to building a diverse and inclusive team.
About MBDF
Founded in 2024, the Mirror Biology Dialogues Fund (MBDF) is a nonprofit dedicated to understanding and averting future risks from "mirror life"—synthetic organisms built from mirror-image versions of the molecules that make up all natural life on Earth.
The risks of mirror bacteria were assessed in a December 2024 Science article and accompanying technical report by a working group of 38 scientists, including two Nobel laureates and 17 members of national academies. The authors concluded that the ecological and health risks of a mirror bacteria release could be unprecedented in scale and called for global discussion to ensure mirror life is never created. The analysis has since been independently reviewed by Germany's Central Committee on Biological Safety (ZKBS), which affirmed the key risk assessments.
These concerns have received serious attention from policymakers and expert bodies. UNESCO's International Bioethics Committee has recommended a precautionary global moratorium on mirror life. The UK government's Chief Scientific Adviser convened a roundtable concluding that an international coalition is needed to prevent the development of mirror organisms. And at the Spirit of Asilomar summit in 2025—convened 50 years after the original Asilomar conference on recombinant DNA—participants reached broad agreement that mirror life should not be created, reinforced by an entreaty signed by 96 attendees.
MBDF’s team includes authors of both the Science article and the accompanying technical report. We support international conferences, workshops, and initiatives to foster constructive dialogue between scientists, policymakers, and civil society. Our goal is to facilitate productive discussion of the challenges presented by mirror life.
To learn more about mirror life and our work, we recommend:
The original Science article (three pages, written for a general audience)
Asimov Press's explainer article with more narrative context
Mirror Life FAQ, with information about developments since December 2024
MBDF’s 2025 Year in Review Newsletter
Descriptions of recent events and outcomes on our Events Page
Selected press coverage: Nature, Financial Times, Le Monde, New York Times, Die Zeit, USA Today.